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Distinct Differences in the Expansion and Phenotype of TB10.4 Specific CD8 and CD4 T Cells after Infection with Mycobacterium tuberculosis

BACKGROUND: Recently we and others have identified CD8 and CD4 T cell epitopes within the highly expressed M. tuberculosis protein TB10.4. This has enabled, for the first time, a comparative study of the dynamics and function of CD4 and CD8 T cells specific for epitopes within the same protein in va...

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Detalles Bibliográficos
Autores principales: Hoang, Truc Thi Kim Thanh, Nansen, Anneline, Roy, Sugata, Billeskov, Rolf, Aagaard, Claus, Elvang, Tara, Dietrich, Jes, Andersen, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691482/
https://www.ncbi.nlm.nih.gov/pubmed/19529765
http://dx.doi.org/10.1371/journal.pone.0005928