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Steroid hormones affect binding of the sigma ligand (11)C-SA4503 in tumour cells and tumour-bearing rats

PURPOSE: Sigma receptors are implicated in memory and cognitive functions, drug addiction, depression and schizophrenia. In addition, sigma receptors are strongly overexpressed in many tumours. Although the natural ligands are still unknown, steroid hormones are potential candidates. Here, we examin...

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Detalles Bibliográficos
Autores principales: Rybczynska, Anna A., Elsinga, Philip H., Sijbesma, Jurgen W., Ishiwata, Kiichi, de Jong, Johan R., de Vries, Erik F., Dierckx, Rudi A., van Waarde, Aren
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691528/
https://www.ncbi.nlm.nih.gov/pubmed/19247652
http://dx.doi.org/10.1007/s00259-009-1076-2