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Differential Effects of Iodoacetamide and Iodoacetate on Glycolysis and Glutathione Metabolism of Cultured Astrocytes

Iodoacetamide (IAA) and iodoacetate (IA) have frequently been used to inhibit glycolysis, since these compounds are known for their ability to irreversibly inhibit the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). However, the consequences of a treatment with such thiol reagent...

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Detalles Bibliográficos
Autores principales: Schmidt, Maike M., Dringen, Ralf
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691547/
https://www.ncbi.nlm.nih.gov/pubmed/19584905
http://dx.doi.org/10.3389/neuro.14.001.2009