Modulation of Gene Expression by Human Cytosolic tRNase Z(L) through 5′-Half-tRNA

A long form (tRNase Z(L)) of tRNA 3′ processing endoribonuclease (tRNase Z, or 3′ tRNase) can cleave any target RNA at any desired site under the direction of artificial small guide RNA (sgRNA) that mimics a 5′-half portion of tRNA. Based on this enzymatic property, a gene silencing technology has b...

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Detalles Bibliográficos
Autores principales: Elbarbary, Reyad A., Takaku, Hiroaki, Uchiumi, Naoto, Tamiya, Hiroko, Abe, Mayumi, Takahashi, Masayuki, Nishida, Hiroshi, Nashimoto, Masayuki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691602/
https://www.ncbi.nlm.nih.gov/pubmed/19526060
http://dx.doi.org/10.1371/journal.pone.0005908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691602/
https://www.ncbi.nlm.nih.gov/pubmed/19526060
http://dx.doi.org/10.1371/journal.pone.0005908

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