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TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4(+ )T cells

BACKGROUND: Recognition of microbial products through Toll-like receptors (TLRs) initiates inflammatory responses orchestrated by innate immune cells such as dendritic cells (DCs). As these cells are patrolling mucosal surfaces, a portal of entry for various pathogens including human immunodeficienc...

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Detalles Bibliográficos
Autores principales: Thibault, Sandra, Fromentin, Rémi, Tardif, Mélanie R, Tremblay, Michel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691729/
https://www.ncbi.nlm.nih.gov/pubmed/19419540
http://dx.doi.org/10.1186/1742-4690-6-42