Application of prolonged microdialysis sampling in carboplatin-treated cancer patients

PURPOSE: To better understand the mechanisms underlying (in)sensitivity of tumors to anticancer drugs, assessing intra-tumor drug pharmacokinetics (PKs) could be important. We explored the feasibility of microdialysis in tumor tissue for multiple days in a clinical setting, using carboplatin as mode...

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Detalles Bibliográficos
Autores principales: Konings, Inge R. H. M., Engels, Frederike K., Sleijfer, Stefan, Verweij, Jaap, Wiemer, Erik A. C., Loos, Walter J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691802/
https://www.ncbi.nlm.nih.gov/pubmed/19096847
http://dx.doi.org/10.1007/s00280-008-0898-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691802/
https://www.ncbi.nlm.nih.gov/pubmed/19096847
http://dx.doi.org/10.1007/s00280-008-0898-0

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