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A recurrent magnesium-binding motif provides a framework for the ribosomal peptidyl transferase center

The ribosome is an ancient macromolecular machine responsible for the synthesis of all proteins in all living organisms. Here we demonstrate that the ribosomal peptidyl transferase center (PTC) is supported by a framework of magnesium microclusters (Mg(2+)-μc's). Common features of Mg(2+)-μc�...

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Detalles Bibliográficos
Autores principales: Hsiao, Chiaolong, Williams, Loren Dean
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691814/
https://www.ncbi.nlm.nih.gov/pubmed/19279186
http://dx.doi.org/10.1093/nar/gkp119