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Structural insights into the cooperative binding of SeqA to a tandem GATC repeat
SeqA is a negative regulator of DNA replication in Escherichia coli and related bacteria that functions by sequestering the origin of replication and facilitating its resetting after every initiation event. Inactivation of the seqA gene leads to unsynchronized rounds of replication, abnormal localiz...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691817/ https://www.ncbi.nlm.nih.gov/pubmed/19304745 http://dx.doi.org/10.1093/nar/gkp151 |