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Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A
The mitochondrial transcription factor A (mtTFA) is central to assembly and initiation of the mitochondrial transcription complex. Human mtTFA (h-mtTFA) is a dual high mobility group box (HMGB) protein that binds site-specifically to the mitochondrial genome and demarcates the promoters for recruitm...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691818/ https://www.ncbi.nlm.nih.gov/pubmed/19304746 http://dx.doi.org/10.1093/nar/gkp157 |