The structure of the human tRNA(Lys3) anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs

Replication of human immunodeficiency virus (HIV) requires base pairing of the reverse transcriptase primer, human tRNA(Lys3), to the viral RNA. Although the major complementary base pairing occurs between the HIV primer binding sequence (PBS) and the tRNA's 3′-terminus, an important discrimina...

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Detalles Bibliográficos
Autores principales: Bilbille, Yann, Vendeix, Franck A. P., Guenther, Richard, Malkiewicz, Andrzej, Ariza, Xavier, Vilarrasa, Jaume, Agris, Paul F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691828/
https://www.ncbi.nlm.nih.gov/pubmed/19324888
http://dx.doi.org/10.1093/nar/gkp187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691828/
https://www.ncbi.nlm.nih.gov/pubmed/19324888
http://dx.doi.org/10.1093/nar/gkp187

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