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A WW-like module in the RAG1 N-terminal domain contributes to previously unidentified protein–protein interactions

More than one-third of the RAG1 protein can be truncated from the N-terminus with only subtle effects on the products of V(D)J recombination in vitro or in a mouse. What, then, is the function of the N-terminal domain? We believe it to be regulatory. We determined, several years ago, that an include...

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Detalles Bibliográficos
Autores principales: Maitra, Radhashree, Sadofsky, Moshe J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691831/
https://www.ncbi.nlm.nih.gov/pubmed/19324890
http://dx.doi.org/10.1093/nar/gkp192