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Involvement of Exo1b in DNA damage-induced apoptosis

Apoptosis is essential for the maintenance of inherited genomic integrity. During DNA damage-induced apoptosis, mechanisms of cell survival, such as DNA repair are inactivated to allow cell death to proceed. Here, we describe a role for the mammalian DNA repair enzyme Exonuclease 1 (Exo1) in DNA dam...

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Detalles Bibliográficos
Autores principales: Bolderson, Emma, Richard, Derek J., Edelmann, Winfried, Khanna, Kum Kum
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691832/
https://www.ncbi.nlm.nih.gov/pubmed/19339515
http://dx.doi.org/10.1093/nar/gkp194