Elevated polyamines induce c-MYC overexpression by perturbing quadruplex–WC duplex equilibrium

The biological role of quadruplexes and polyamines has been independently associated with cancer. However, quadruplex-polyamine mediated transcriptional regulation remain unaddressed. Herein, using c-MYC quadruplex model, we have attempted to understand quadruplex–polyamine interaction and its role...

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Detalles Bibliográficos
Autores principales: Kumar, Niti, Basundra, Richa, Maiti, Souvik
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691834/
https://www.ncbi.nlm.nih.gov/pubmed/19324889
http://dx.doi.org/10.1093/nar/gkp196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691834/
https://www.ncbi.nlm.nih.gov/pubmed/19324889
http://dx.doi.org/10.1093/nar/gkp196

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