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Structural basis for the specialization of Nur, a nickel-specific Fur homolog, in metal sensing and DNA recognition

Nur, a member of the Fur family, is a nickel-responsive transcription factor that controls nickel homeostasis and anti-oxidative response in Streptomyces coelicolor. Here we report the 2.4-Å resolution crystal structure of Nur. It contains a unique nickel-specific metal site in addition to a nonspec...

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Detalles Bibliográficos
Autores principales: An, Young Jun, Ahn, Bo-Eun, Han, A-Reum, Kim, Hae-Mi, Chung, Kyung Min, Shin, Jung-Ho, Cho, Yoo-Bok, Roe, Jung-Hye, Cha, Sun-Shin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691836/
https://www.ncbi.nlm.nih.gov/pubmed/19336416
http://dx.doi.org/10.1093/nar/gkp198