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A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level

The complexity of mammalian transcriptomes is compounded by alternative splicing which allows one gene to produce multiple transcript isoforms. However, transcriptome comparison has been limited to differential analysis at the gene level instead of the individual transcript isoform level. High-throu...

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Detalles Bibliográficos
Autores principales: Zheng, Sika, Chen, Liang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691848/
https://www.ncbi.nlm.nih.gov/pubmed/19417075
http://dx.doi.org/10.1093/nar/gkp282