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A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level
The complexity of mammalian transcriptomes is compounded by alternative splicing which allows one gene to produce multiple transcript isoforms. However, transcriptome comparison has been limited to differential analysis at the gene level instead of the individual transcript isoform level. High-throu...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691848/ https://www.ncbi.nlm.nih.gov/pubmed/19417075 http://dx.doi.org/10.1093/nar/gkp282 |