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Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model
We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED(90)) of PQ and LM against the parent line were 3.52 and 3.93 mg/kg, respectively. After drug pressure (more than 27 p...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691925/ https://www.ncbi.nlm.nih.gov/pubmed/19318094 http://dx.doi.org/10.1016/j.exppara.2009.03.010 |