Protection and Polyfunctional T Cells Induced by Ag85B-TB10.4/IC31® against Mycobacterium tuberculosis Is Highly Dependent on the Antigen Dose

BACKGROUND: Previously we have shown that Ag85B-TB10.4 is a highly efficient vaccine against tuberculosis when delivered in a Th1 inducing adjuvant based on cationic liposomes. Another Th1 inducing adjuvant, which has shown a very promising profile in both preclinical and clinical trials, is IC31®....

Descripción completa

Detalles Bibliográficos
Autores principales: Aagaard, Claus, Hoang, Truc Thi Kim Thanh, Izzo, Angelo, Billeskov, Rolf, Troudt, JoLynn, Arnett, Kim, Keyser, Andrew, Elvang, Tara, Andersen, Peter, Dietrich, Jes
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691953/
https://www.ncbi.nlm.nih.gov/pubmed/19529771
http://dx.doi.org/10.1371/journal.pone.0005930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691953/
https://www.ncbi.nlm.nih.gov/pubmed/19529771
http://dx.doi.org/10.1371/journal.pone.0005930

Ejemplares similares