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Genetic and Proteomic Evidence for Roles of Drosophila SUMO in Cell Cycle Control, Ras Signaling, and Early Pattern Formation

SUMO is a protein modifier that is vital for multicellular development. Here we present the first system-wide analysis, combining multiple approaches, to correlate the sumoylated proteome (SUMO-ome) in a multicellular organism with the developmental roles of SUMO. Using mass-spectrometry-based prote...

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Detalles Bibliográficos
Autores principales: Nie, Minghua, Xie, Yongming, Loo, Joseph A., Courey, Albert J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692000/
https://www.ncbi.nlm.nih.gov/pubmed/19529778
http://dx.doi.org/10.1371/journal.pone.0005905