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Tumours with PI3K activation are resistant to dietary restriction

Dietary restriction (DR) delays the incidence and decreases the growth of various types of tumours, but the mechanisms underlying the sensitivity of tumours to food restriction remain unknown. We find that certain human cancer cell lines, when grown as tumour xenografts in mice, are highly sensitive...

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Detalles Bibliográficos
Autores principales: Kalaany, Nada Y., Sabatini, David M.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692085/
https://www.ncbi.nlm.nih.gov/pubmed/19279572
http://dx.doi.org/10.1038/nature07782