Comparison of the pharmacokinetics, safety and tolerability of daptomycin in healthy adult volunteers following intravenous administration by 30 min infusion or 2 min injection

OBJECTIVES: Two randomized Phase I studies in separate populations of healthy adult volunteers investigated the pharmacokinetics, safety and tolerability of daptomycin (Cubicin(®); Novartis Pharma AG, Basel, Switzerland) administered as a 2 min intravenous (iv) injection, relative to the currently l...

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Detalles Bibliográficos
Autores principales: Chakraborty, Abhijit, Roy, Sandip, Loeffler, Juergen, Chaves, Ricardo L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692502/
https://www.ncbi.nlm.nih.gov/pubmed/19389714
http://dx.doi.org/10.1093/jac/dkp155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692502/
https://www.ncbi.nlm.nih.gov/pubmed/19389714
http://dx.doi.org/10.1093/jac/dkp155

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