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Comparison of the pharmacokinetics, safety and tolerability of daptomycin in healthy adult volunteers following intravenous administration by 30 min infusion or 2 min injection
OBJECTIVES: Two randomized Phase I studies in separate populations of healthy adult volunteers investigated the pharmacokinetics, safety and tolerability of daptomycin (Cubicin(®); Novartis Pharma AG, Basel, Switzerland) administered as a 2 min intravenous (iv) injection, relative to the currently l...
Autores principales: | Chakraborty, Abhijit, Roy, Sandip, Loeffler, Juergen, Chaves, Ricardo L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692502/ https://www.ncbi.nlm.nih.gov/pubmed/19389714 http://dx.doi.org/10.1093/jac/dkp155 |
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