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Tyrosine Dephosphorylation of H2AX Modulates Apoptosis and Survival Decisions

Life and death fate decisions allow cells to avoid massive apoptotic death in response to genotoxic stress. While the regulatory mechanisms and signaling pathways controlling DNA repair and apoptosis are well characterized, the precise molecular strategies that determine the ultimate choice of DNA r...

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Detalles Bibliográficos
Autores principales: Cook, Peter J., Ju, Bong Gun, Telese, Francesca, Wang, Xiangting, Glass, Christopher K., Rosenfeld, Michael G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692521/
https://www.ncbi.nlm.nih.gov/pubmed/19234442
http://dx.doi.org/10.1038/nature07849