The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines

BACKGROUND: The overall level of chromatin compaction is an important mechanism of radiosensitivity, and modification of DNA methylation and histone deacetylation may increase radiosensitivity by altering chromatin compaction. In this study, we investigated the effect of a demethylating agent, a his...

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Detalles Bibliográficos
Autores principales: Cho, Hang Joo, Kim, Sin Young, Kim, Kee Hwan, Kang, Won Kyung, kim, Ji Il, Oh, Seong Tack, Kim, Jeong Soo, An, Chang Hyeok
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692973/
https://www.ncbi.nlm.nih.gov/pubmed/19460134
http://dx.doi.org/10.1186/1477-7819-7-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692973/
https://www.ncbi.nlm.nih.gov/pubmed/19460134
http://dx.doi.org/10.1186/1477-7819-7-49

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