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The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2

The cellular receptor for human coronavirus NL63 (HCoV-NL63), a group I coronavirus, is angiotensin-converting enzyme2 (ACE2). ACE2 is also the receptor for the SARS coronavirus (SARS-CoV), a group II coronavirus. Here we describe the ability of HCoV-NL63 to utilize a number of ACE2 variants previou...

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Detalles Bibliográficos
Autores principales: Li, Wenhui, Sui, Jianhua, Huang, I-Chueh, Kuhn, Jens H., Radoshitzky, Sheli R., Marasco, Wayne A., Choe, Hyeryun, Farzan, Michael
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693060/
https://www.ncbi.nlm.nih.gov/pubmed/17631932
http://dx.doi.org/10.1016/j.virol.2007.04.035