Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

Vaginal instillation of small-interfering RNA (siRNA) using liposomes has led to silencing of endogenous genes in the genital tract and protected against challenge from infectious disease. Although siRNA lipoplexes are easily formulated, several of the most effective transfection agents available co...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodrow, Kim A., Cu, Yen, Booth, Carmen J., Saucier-Sawyer, Jennifer K., Wood, Monica J., Saltzman, W. Mark
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693358/
https://www.ncbi.nlm.nih.gov/pubmed/19404239
http://dx.doi.org/10.1038/nmat2444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693358/
https://www.ncbi.nlm.nih.gov/pubmed/19404239
http://dx.doi.org/10.1038/nmat2444

Ejemplares similares