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Robust MS quantification method for phospho-peptides using (18)O/(16)O labeling

BACKGROUND: Quantitative measurements of specific protein phosphorylation sites, as presented here, can be used to investigate signal transduction pathways, which is an important aspect of cell dynamics. The presented method quantitatively compares peptide abundances from experiments using (18)O/(16...

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Detalles Bibliográficos
Autores principales: Andersen, Claus A, Gotta, Stefano, Magnoni, Letizia, Raggiaschi, Roberto, Kremer, Andreas, Terstappen, Georg C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693437/
https://www.ncbi.nlm.nih.gov/pubmed/19432989
http://dx.doi.org/10.1186/1471-2105-10-141