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Limbic Epileptogenesis in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS), caused by silencing of the Fmr1 gene, is the most common form of inherited mental retardation. Epilepsy is reported to occur in 20–25% of individuals with FXS. However, no overall increased excitability has been reported in Fmr1 knockout (KO) mice, except for increased sens...

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Detalles Bibliográficos
Autores principales: Qiu, Li-Feng, Lu, Ting-Jia, Hu, Xiao-Ling, Yi, Yong-Hong, Liao, Wei-Ping, Xiong, Zhi-Qi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693616/
https://www.ncbi.nlm.nih.gov/pubmed/18832330
http://dx.doi.org/10.1093/cercor/bhn163