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Limbic Epileptogenesis in a Mouse Model of Fragile X Syndrome
Fragile X syndrome (FXS), caused by silencing of the Fmr1 gene, is the most common form of inherited mental retardation. Epilepsy is reported to occur in 20–25% of individuals with FXS. However, no overall increased excitability has been reported in Fmr1 knockout (KO) mice, except for increased sens...
Autores principales: | Qiu, Li-Feng, Lu, Ting-Jia, Hu, Xiao-Ling, Yi, Yong-Hong, Liao, Wei-Ping, Xiong, Zhi-Qi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693616/ https://www.ncbi.nlm.nih.gov/pubmed/18832330 http://dx.doi.org/10.1093/cercor/bhn163 |
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