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Pyramidal Neurons in Rat Prefrontal Cortex Projecting to Ventral Tegmental Area and Dorsal Raphe Nucleus Express 5-HT(2A) Receptors

The prefrontal cortex (PFC) is involved in higher brain functions altered in schizophrenia. Classical antipsychotics modulate cortico-limbic circuits mainly through subcortical D2 receptor blockade, whereas second generation (atypical) antipsychotics preferentially target cortical 5-HT receptors. An...

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Detalles Bibliográficos
Autores principales: Vázquez-Borsetti, Pablo, Cortés, Roser, Artigas, Francesc
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693622/
https://www.ncbi.nlm.nih.gov/pubmed/19029064
http://dx.doi.org/10.1093/cercor/bhn204