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Structure and functional relevance of the Slit2 homodimerization domain

Slit proteins are secreted ligands that interact with the Roundabout (Robo) receptors to provide important guidance cues in neuronal and vascular development. Slit–Robo signalling is mediated by an interaction between the second Slit domain and the first Robo domain, as well as being dependent on he...

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Detalles Bibliográficos
Autores principales: Seiradake, Elena, von Philipsborn, Anne C, Henry, Maud, Fritz, Martin, Lortat-Jacob, Hugues, Jamin, Marc, Hemrika, Wieger, Bastmeyer, Martin, Cusack, Stephen, McCarthy, Andrew A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693880/
https://www.ncbi.nlm.nih.gov/pubmed/19498462
http://dx.doi.org/10.1038/embor.2009.95