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Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies

To study the substrate specificity of enzymes, we use the amidohydrolase and enolase superfamilies as model systems; members of these superfamilies share a common TIM barrel fold and catalyze a wide range of chemical reactions. Here, we describe a collaboration between the Enzyme Specificity Consort...

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Detalles Bibliográficos
Autores principales: Pieper, Ursula, Chiang, Ranyee, Seffernick, Jennifer J., Brown, Shoshana D., Glasner, Margaret E., Kelly, Libusha, Eswar, Narayanan, Sauder, J. Michael, Bonanno, Jeffrey B., Swaminathan, Subramanyam, Burley, Stephen K., Zheng, Xiaojing, Chance, Mark R., Almo, Steven C., Gerlt, John A., Raushel, Frank M., Jacobson, Matthew P., Babbitt, Patricia C., Sali, Andrej
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693957/
https://www.ncbi.nlm.nih.gov/pubmed/19219566
http://dx.doi.org/10.1007/s10969-008-9056-5