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c-Myc Accelerates S-Phase and Requires WRN to Avoid Replication Stress
c-Myc interacts with components of the pre-replication complex and directly regulates DNA replication [1]. However the consequences of this novel c-Myc function on cell cycle dynamics and replication-associated damage are unknown. Here, we show that c-Myc overexpression in primary human fibroblasts...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694031/ https://www.ncbi.nlm.nih.gov/pubmed/19554081 http://dx.doi.org/10.1371/journal.pone.0005951 |