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Heterologous cross-seeding mimics cross-species prion conversion in a yeast model
BACKGROUND: Prions are self-perpetuating, infectious, aggregated proteins that are associated with several neurodegenerative diseases in mammals and heritable traits in yeast. Sup35p, the protein determinant of the yeast prion [PSI(+)], has a conserved C terminal domain that performs the Sup35p func...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694167/ https://www.ncbi.nlm.nih.gov/pubmed/19470166 http://dx.doi.org/10.1186/1741-7007-7-26 |