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Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection
BACKGROUND: Methodologies like phage display selection, in vitro mutagenesis and the determination of allelic expression differences include steps where large numbers of clones need to be compared and characterised. In the current study we show that high-resolution melt curve analysis (HRMA) is a si...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694173/ https://www.ncbi.nlm.nih.gov/pubmed/19463169 http://dx.doi.org/10.1186/1472-6750-9-50 |