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Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicing

BACKGROUND: Human sex hormone-binding globulin (SHBG) regulates free sex steroid concentrations in plasma and modulates rapid, membrane based steroid signaling. SHBG is encoded by an eight exon-long transcript whose expression is regulated by a downstream promoter (P(L)). The SHBG gene was previousl...

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Detalles Bibliográficos
Autores principales: Nakhla, Atif M, Hryb, Daniel J, Rosner, William, Romas, Nicholas A, Xiang, Zhaoying, Kahn, Scott M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694190/
https://www.ncbi.nlm.nih.gov/pubmed/19416531
http://dx.doi.org/10.1186/1471-2199-10-37