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Evolution of Mutational Robustness in the Yeast Genome: A Link to Essential Genes and Meiotic Recombination Hotspots

Deleterious mutations inevitably emerge in any evolutionary process and are speculated to decisively influence the structure of the genome. Meiosis, which is thought to play a major role in handling mutations on the population level, recombines chromosomes via non-randomly distributed hot spots for...

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Detalles Bibliográficos
Autores principales: Keller, Philipp J., Knop, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694357/
https://www.ncbi.nlm.nih.gov/pubmed/19557188
http://dx.doi.org/10.1371/journal.pgen.1000533