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Cancer risks in first-degree relatives of CHEK2 mutation carriers: effects of mutation type and cancer site in proband

It is important to have accurate knowledge of the range of cancers associated with various CHEK2 mutations, and of the lifetime risks of cancer associated with each. We wished to establish the relationship between family history, mutation type and cancer risk in families with a CHEK2 mutation. We ob...

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Detalles Bibliográficos
Autores principales: Gronwald, J, Cybulski, C, Piesiak, W, Suchy, J, Huzarski, T, Byrski, T, Gorski, B, Debniak, T, Szwiec, M, Wokolowczyk, D, Matuszewski, M, Sun, P, Lubinski, J, Narod, S A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694428/
https://www.ncbi.nlm.nih.gov/pubmed/19401704
http://dx.doi.org/10.1038/sj.bjc.6605038