ERK-1/-2 and p38 Kinase Oppositely Regulate 15-deoxy-Δ(12,14)-prostaglandinJ(2)-Induced PPAR-γ Activation That Mediates Dedifferentiation But Not Cyclooxygenase-2 Expression in Articular Chondrocytes

Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a ligand-activated transcription factor and plays an important role in growth, differentiation, and inflammation in different tissues. In this study, we investigated the effects of 15d-PGJ(2), a high-affinity ligand of PPAR-γ, on dediffere...

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Detalles Bibliográficos
Autores principales: Yoon, Eun-Kyung, Lee, Won-Kil, Lee, Ji-Hye, Yu, Seon-Mi, Hwang, Sang-Gu, Kim, Song-Ja
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2007
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694644/
https://www.ncbi.nlm.nih.gov/pubmed/18162716
http://dx.doi.org/10.3346/jkms.2007.22.6.1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694644/
https://www.ncbi.nlm.nih.gov/pubmed/18162716
http://dx.doi.org/10.3346/jkms.2007.22.6.1015

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