Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

The molecular complexity of mammalian proteomes demands new methods for mapping the organization of multiprotein complexes. Here, we combine mouse genetics and proteomics to characterize synapse protein complexes and interaction networks. New tandem affinity purification (TAP) tags were fused to the...

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Detalles Bibliográficos
Autores principales: Fernández, Esperanza, Collins, Mark O, Uren, Rachel T, Kopanitsa, Maksym V, Komiyama, Noboru H, Croning, Mike D R, Zografos, Lysimachos, Armstrong, J Douglas, Choudhary, Jyoti S, Grant, Seth G N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694677/
https://www.ncbi.nlm.nih.gov/pubmed/19455133
http://dx.doi.org/10.1038/msb.2009.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694677/
https://www.ncbi.nlm.nih.gov/pubmed/19455133
http://dx.doi.org/10.1038/msb.2009.27

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