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Protein sequestration generates a flexible ultrasensitive response in a genetic network
Ultrasensitive responses are crucial for cellular regulation. Protein sequestration, where an active protein is bound in an inactive complex by an inhibitor, can potentially generate ultrasensitivity. Here, in a synthetic genetic circuit in budding yeast, we show that sequestration of a basic leucin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694680/ https://www.ncbi.nlm.nih.gov/pubmed/19455136 http://dx.doi.org/10.1038/msb.2009.30 |