Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2

BACKGROUND: Recent evidence suggests that several human cancers are capable of uncoupling of mitochondrial ATP generation in the presence of intact tricarboxylic acid (TCA) enzymes. The goal of the current study was to test the hypothesis that ketone bodies can inhibit cell growth in aggressive canc...

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Detalles Bibliográficos
Autores principales: Fine, Eugene J, Miller, Anna, Quadros, Edward V, Sequeira, Jeffrey M, Feinman, Richard D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694762/
https://www.ncbi.nlm.nih.gov/pubmed/19480693
http://dx.doi.org/10.1186/1475-2867-9-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694762/
https://www.ncbi.nlm.nih.gov/pubmed/19480693
http://dx.doi.org/10.1186/1475-2867-9-14

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