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Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2
BACKGROUND: Recent evidence suggests that several human cancers are capable of uncoupling of mitochondrial ATP generation in the presence of intact tricarboxylic acid (TCA) enzymes. The goal of the current study was to test the hypothesis that ketone bodies can inhibit cell growth in aggressive canc...
Autores principales: | Fine, Eugene J, Miller, Anna, Quadros, Edward V, Sequeira, Jeffrey M, Feinman, Richard D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694762/ https://www.ncbi.nlm.nih.gov/pubmed/19480693 http://dx.doi.org/10.1186/1475-2867-9-14 |
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