Cargando…

Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells

BACKGROUND: Maintaining the correct balance of proliferation versus differentiation in retinal progenitor cells (RPCs) is essential for proper development of the retina. The cell cycle regulator cyclin D1 is expressed in RPCs, and mice with a targeted null allele at the cyclin D1 locus (Ccnd1(-/-))...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Gaurav, Choi, Yoon, Sicinski, Piotr, Levine, Edward M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694796/
https://www.ncbi.nlm.nih.gov/pubmed/19416500
http://dx.doi.org/10.1186/1749-8104-4-15