Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

BACKGROUND: Dihydroartemisinin (DHA), a powerful anti-malarial drug, has been used as monotherapy and artemisinin-based combination therapy (ACT) for more than decades. So far, however, the tissue distribution and metabolic profile of DHA data are not available from animal and humans. METHODS: Pharm...

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Detalles Bibliográficos
Autores principales: Xie, Lisa H, Li, Qigui, Zhang, Jing, Weina, Peter J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694832/
https://www.ncbi.nlm.nih.gov/pubmed/19470172
http://dx.doi.org/10.1186/1475-2875-8-112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694832/
https://www.ncbi.nlm.nih.gov/pubmed/19470172
http://dx.doi.org/10.1186/1475-2875-8-112

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