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Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats
BACKGROUND: Dihydroartemisinin (DHA), a powerful anti-malarial drug, has been used as monotherapy and artemisinin-based combination therapy (ACT) for more than decades. So far, however, the tissue distribution and metabolic profile of DHA data are not available from animal and humans. METHODS: Pharm...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694832/ https://www.ncbi.nlm.nih.gov/pubmed/19470172 http://dx.doi.org/10.1186/1475-2875-8-112 |