Rapid Insulin-Dependent Endocytosis of the Insulin Receptor by Caveolae in Primary Adipocytes

BACKGROUND: The insulin receptor is localized in caveolae and is dependent on caveolae or cholesterol for signaling in adipocytes. When stimulated with insulin, the receptor is internalized. METHODOLOGY/PRINCIPAL FINDINGS: We examined primary rat adipocytes by subcellular fractionation to examine if...

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Detalles Bibliográficos
Autores principales: Fagerholm, Siri, Örtegren, Unn, Karlsson, Margareta, Ruishalme, Iida, Strålfors, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695004/
https://www.ncbi.nlm.nih.gov/pubmed/19543529
http://dx.doi.org/10.1371/journal.pone.0005985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695004/
https://www.ncbi.nlm.nih.gov/pubmed/19543529
http://dx.doi.org/10.1371/journal.pone.0005985

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