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Elevated Serum Levels of Arachidonoyl-lysophosphatidic Acid and Sphingosine 1-Phosphate in Systemic Sclerosis

Systemic sclerosis (SSc) is an often fatal disease characterized by autoimmunity and inflammation, leading to widespread vasculopathy and fibrosis. Lysophosphatidic acid (LPA), a bioactive phospholipid in serum, is generated from lysophospholipids secreted from activated platelets in part by the act...

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Detalles Bibliográficos
Autores principales: Tokumura, Akira, Carbone, Laura D., Yoshioka, Yasuko, Morishige, Junichi, Kikuchi, Masaki, Postlethwaite, Arnold, Watsky, Mitchell A.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695151/
https://www.ncbi.nlm.nih.gov/pubmed/19521548