Role of protein kinase C and μ-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons

In morphine tolerance a key question that remains to be answered is whether μ-opioid receptor (MOPr) desensitization contributes to morphine tolerance, and if so by what cellular mechanisms. Here we demonstrate that MOPr desensitization can be observed in single rat brainstem locus coeruleus (LC) ne...

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Detalles Bibliográficos
Autores principales: Bailey, C P, Llorente, J, Gabra, B H, Smith, F L, Dewey, W L, Kelly, E, Henderson, G
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Synaptic Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695152/
https://www.ncbi.nlm.nih.gov/pubmed/19200236
http://dx.doi.org/10.1111/j.1460-9568.2008.06573.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695152/
https://www.ncbi.nlm.nih.gov/pubmed/19200236
http://dx.doi.org/10.1111/j.1460-9568.2008.06573.x

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