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The 14-3-3σ gene promoter is methylated in both human melanocytes and melanoma
BACKGROUND: Recent evidence demonstrates that 14-3-3σ acts as a tumor suppressor gene inactivated by methylation of its 5' CpG islands in epithelial tumor cells, while remaining un-methylated in normal human epithelia. The methylation analysis of 14-3-3σ has been largely overlooked in melanoma....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695475/ https://www.ncbi.nlm.nih.gov/pubmed/19473536 http://dx.doi.org/10.1186/1471-2407-9-162 |