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Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma

BACKGROUND: Flat epithelial atypia (FEA) of the breast is characterised by a few layers of mildly atypical luminal epithelial cells. Genetic changes found in ductal carcinoma in situ (DCIS) and invasive ductal breast cancer (IDC) are also found in FEA, albeit at a lower concentration. So far, miRNA...

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Detalles Bibliográficos
Autores principales: Qi, Liqiang, Bart, Joost, Tan, Lu Ping, Platteel, Inge, Sluis, Tineke van der, Huitema, Sippie, Harms, Geert, Fu, Li, Hollema, Harry, Berg, Anke van den
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695476/
https://www.ncbi.nlm.nih.gov/pubmed/19473551
http://dx.doi.org/10.1186/1471-2407-9-163